Four well-named, read-only tools with complete input schemas and strong descriptions (avg 180 chars). All parameters are typed and described. Tool names follow verb_noun pattern (search_*, target_interactions, ligand_interactions). Descriptions clearly state purpose, use case, and relationship to other tools. However, output schemas are not formally documented, only inferred from code. Error handling returns generic error objects without recovery guidance. No parameter constraints (enums, ranges) despite opportunities (e.g., limit defaults). Missing tool annotations (readOnlyHint). Composition is sound: search tools feed into interaction tools via ID chaining.

• Add formal outputSchema to each tool definition. Example for search_ligands: {type: 'object', properties: {count: {type: 'number'}, ligands: {type: 'array', items: {type: 'object', properties: {id: {type: 'number'}, name: {type: 'string'}, type: {type: 'string'}, approved: {type: 'boolean'}, abbreviation: {type: 'string'}}}}}}.
• Enhance error handling: catch specific HTTP status codes (404, 429, 500) and return {error: string, code: string, retryable: boolean, suggestion: string}. E.g., 404 → 'Ligand not found. Try search_ligands() with a partial name.'
• Add readOnlyHint: true to all four tool definitions to signal safety to clients.
• Constrain limit parameter: {type: 'number', minimum: 1, maximum: 100, description: 'Max results to return (default 15). Must be 1 - 100.'}
• Add total_count to search responses and implement offset-based pagination: accept optional offset parameter, return {count: total_count, offset, limit, ligands/targets} so LLM can fetch subsequent pages.